The GSENSE400BSI sensor is a 4 Megapixels resolution BSI CMOS image sensor with 11μm pixel size. As the first backside illuminated scientific CMOS image sensor in the world, GSENSE400BSI features low readout noise of 1.6 e ˉ, high dynamic range of 94dB, and low dark current of 0.27e-/s/pix at deep cooling of -40℃.